I am not left handed, but my wife is. There is a distinct difference in the way we perceive things, the way we manipulate objects and even the way we interact with the world around us.
The world is right handed, and I often feel sorry that my wife has to move through a society that is unsympathetic and alien to her natural inclinations.
I could make a list; but it is better expressed by Salman Rushdie in Luka and the Fire of Life.
Door knobs turn the wrong way. Screws insist on being turned clockwise, guitars were strung upside down, and the scripts in which most languages were written ran awkwardly from left to right… Potter wheels wheeled perversely, dervishes would have whirled better if they whirled in the opposite direction, and how much finer and more sensible the whole world would be, Luka thought, if the sun rose in the west and set in the east.
Seeing things in reverse to accepted norms is a special gift that results in innovation. Some of our most brilliant people, and I include my wife, were and are left handed.